B12 is a research compound supplied by Badger Compounds for laboratory use only and is not intended for human or animal consumption.

B12 (Cyanocobalamin)

Overview

B12, also known as cyanocobalamin, is a water-soluble cobalamin research compound supplied by Badger Compounds for laboratory use only. It is studied for its role as a cofactor in cellular biochemical processes within controlled laboratory and in vitro settings.

Cobalamins are among the most structurally complex small molecules in biology, built around a central cobalt ion held within a corrin ring. This distinctive architecture makes B12 a frequently referenced compound in enzymatic and methylation research.

Researchers incorporate B12 into cell and biochemical models examining methylation-related signaling, DNA-associated pathways, and mitochondrial enzymatic activity. Its well-documented chemistry supports reproducible experimental design.

Every lot of B12 from Badger Compounds is characterized to a purity of ≥99% (HPLC) and verified by independent third-party analytical testing, supporting consistent and reliable research conditions.

B12 Molecular Research Context

In published research models, B12 serves as an essential cofactor for two principal enzyme families. As methylcobalamin, it supports methionine synthase in methylation reactions, and as adenosylcobalamin it supports methylmalonyl-CoA mutase in mitochondrial metabolism.

Cyanocobalamin is a stable form that is converted within cellular systems to these active cofactor states. Researchers study these conversions and the downstream effects on one-carbon metabolism and cellular energy pathways. All described observations are confined to in vitro and research settings and do not represent clinical outcomes.

Additional Research Considerations

Investigators evaluating this compound often review the broader cobalamin and one-carbon metabolism literature to contextualize their findings. A current overview of relevant publications can be found through the PubMed database, which indexes peer-reviewed studies describing B12 in experimental systems.

Research Applications

• Investigation of methylation-related signaling and one-carbon metabolism in cultured cells
• Studies of cobalamin-dependent enzyme activity in laboratory models
• Mitochondrial and cellular energy research involving cofactor pathways
• Reference standard work alongside related metabolic research compounds
• Method development for analytical detection of cobalamin compounds

Product Specifications

• Form: Lyophilized powder
• Purity: ≥99% (HPLC)
• Quantity: 10 mg per vial (single vial and 10-vial options)
• Molecular Weight: 1355.37 g/mol
• CAS Number: 68-19-9
• Molecular Formula: C63H88CoN14O14P
• Type: Water-soluble cobalamin (Vitamin B12)
• Solubility: Soluble in water for laboratory preparation
• Characterization: Identity and purity confirmed by HPLC and appropriate analytical methods
• Testing: Independent third-party analytical verification

Storage and Handling

Lyophilized B12 should be stored at -20°C and protected from light and moisture, as cobalamins are light sensitive. Once reconstituted in a laboratory setting, the solution is best kept refrigerated at 2°C to 8°C, protected from light, and used within a short working window. Handling should follow standard laboratory safety practices, including the use of appropriate personal protective equipment. This material is intended for qualified research personnel only.

Related Research Compounds

Laboratories studying cellular energy and metabolic pathways frequently pair B12 with related research compounds such as NAD+, Glutathione, and AICAR. Browse the full research compounds catalog for additional products.

Frequently Asked Questions

What is B12?
B12 (cyanocobalamin) is a water-soluble cobalamin compound studied as a cofactor in cellular biochemical research. It is supplied strictly as a research compound for laboratory use.

What purity is this B12?
Each lot is characterized to ≥99% (HPLC) purity and confirmed through independent third-party testing.

How should B12 be stored?
Store the lyophilized powder at -20°C away from light and moisture, and refrigerate any reconstituted solution prepared in the laboratory, protected from light.

Disclaimer

This product is intended for laboratory and research use only. It is not a drug, food, cosmetic, or dietary supplement, and it is not intended to diagnose, treat, cure, or prevent any disease. It is not for human or veterinary use or consumption in any form. All information provided is for educational and research purposes only and does not constitute medical advice. By purchasing, the buyer confirms they are a qualified researcher or institution and accepts full responsibility for safe handling, use, and disposal in compliance with applicable laws and regulations.