VIP is a research peptide supplied by Badger Compounds for laboratory use only and is not intended for human or animal consumption.

VIP (Vasoactive Intestinal Peptide)

Overview

VIP, or vasoactive intestinal peptide, is a 28-amino-acid neuropeptide supplied by Badger Compounds for laboratory use only. This research peptide is studied across neurological, immunological, and gastrointestinal signaling models in controlled laboratory settings.

The molecule belongs to the secretin and glucagon peptide superfamily and is widely distributed throughout the central and peripheral nervous systems. It functions as a neurotransmitter and neuroendocrine releasing factor in vertebrate tissues.

Researchers select VIP as a defined tool peptide when investigating receptor signaling, smooth muscle physiology, and immune modulation in vitro. Its well-documented sequence supports reproducible experimental design.

Every lot of VIP from Badger Compounds is characterized to a purity of ≥99% (HPLC) and verified by independent third-party analytical testing, supporting consistent and reliable research conditions.

VIP Receptor Interaction Research Context

In published research models, VIP binds the class II G protein-coupled receptors VPAC1 and VPAC2, which are expressed widely across the nervous, digestive, respiratory, and immune systems. Receptor engagement activates adenylate cyclase and raises intracellular cyclic AMP.

This signaling is studied for its association with smooth muscle relaxation, secretion, and the modulation of immune-cell activity in laboratory systems. The shared affinity of VIP for both receptor subtypes makes it a useful reference ligand in receptor research. All described observations are confined to in vitro and research settings and do not represent clinical outcomes.

Additional Research Considerations

Investigators evaluating this peptide often review the broader VIP and PACAP signaling literature to contextualize their findings. A current overview of relevant publications can be found through the PubMed database, which indexes peer-reviewed studies describing VIP in experimental systems.

Research Applications

• Investigation of VPAC1 and VPAC2 receptor activation and cAMP signaling in cultured cells
• Studies of smooth muscle physiology and secretory pathways in vitro
• Immune modulation and neuroinflammation research in controlled laboratory environments
• Reference standard work alongside related neuropeptide research compounds
• Method development for analytical detection of secretin-family peptides

Product Specifications

• Form: Lyophilized powder
• Purity: ≥99% (HPLC)
• Quantity: 10 mg per vial (single vial and 10-vial options)
• Molecular Weight: Approximately 3326 Da
• CAS Number: 37221-79-7
• Sequence: 28-amino-acid neuropeptide (secretin / glucagon superfamily)
• Solubility: Soluble in compatible aqueous buffers
• Characterization: Identity and purity confirmed by HPLC and mass spectrometry
• Testing: Independent third-party analytical verification

Storage and Handling

Lyophilized VIP should be stored at -20°C and protected from light and moisture. Once reconstituted in a laboratory setting, the solution is best kept refrigerated at 2°C to 8°C and used within a short working window. Handling should follow standard laboratory safety practices, including the use of appropriate personal protective equipment. This material is intended for qualified research personnel only.

Related Research Compounds

Laboratories studying neuropeptide and immune signaling pathways frequently pair VIP with related research peptides such as KPV, LL-37, and Thymosin Alpha-1. Browse the full research peptides catalog for additional compounds.

Frequently Asked Questions

What is VIP?
VIP (vasoactive intestinal peptide) is a 28-amino-acid neuropeptide of the secretin and glucagon superfamily studied in neurological and immune research. It is supplied strictly as a research peptide for laboratory use.

What purity is this VIP?
Each lot is characterized to ≥99% (HPLC) purity and confirmed through independent third-party testing.

How should VIP be stored?
Store the lyophilized powder at -20°C away from light and moisture, and refrigerate any reconstituted solution prepared in the laboratory.

Disclaimer

This product is intended for laboratory and research use only. It is not a drug, food, cosmetic, or dietary supplement, and it is not intended to diagnose, treat, cure, or prevent any disease. It is not for human or veterinary use or consumption in any form. All information provided is for educational and research purposes only and does not constitute medical advice. By purchasing, the buyer confirms they are a qualified researcher or institution and accepts full responsibility for safe handling, use, and disposal in compliance with applicable laws and regulations.